Description

2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a heterocyclic organic compound featuring a fused pyridine and pyrimidine ring system, serving as a versatile and high-value pharmaceutical intermediate. Its molecular scaffold is crucial for medicinal chemistry research, particularly in the development of kinase inhibitors and other targeted therapeutic agents. This compound is primarily sought by R&D departments and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors for synthesizing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged scaffold.
• Biochemical Tool Compound: Serves as a core structure for developing probes and assay standards in biological testing.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS No.	1159882-42-4
Molecular Formula	C9H11N3
Molecular Weight	161.21 g/mol
Synonyms	2-Methyl-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidine; 2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; Pyrido[3,4-d]pyrimidine, 5,6,7,8-tetrahydro-2-methyl-; 5,6,7,8-Tetrahydro-2-methylpyrido[3,4-d]pyrimidine; 2-Methyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.