Description

1-(Pyrimidin-2-Yl)Cyclopropanamine is a high-purity, functionalized cyclopropane building block featuring a pyrimidine heterocycle. This compound is of significant value in pharmaceutical and agrochemical research as a key intermediate for constructing novel molecules with potential biological activity. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique fused ring structure for bioactivity.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology: Employed as a probe or linker in the design of chemical tools for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(Pyrimidin-2-Yl)Cyclopropanamine
CAS No.	1159878-06-4
Molecular Formula	C7H9N3
Molecular Weight	135.17 g/mol
Synonyms	1-(Pyrimidin-2-yl)cyclopropanamine; 1-(2-Pyrimidinyl)cyclopropanamine; 2-(1-Aminocyclopropyl)pyrimidine; Cyclopropanamine, 1-(2-pyrimidinyl)-; 1-Amino-1-(pyrimidin-2-yl)cyclopropane; 1-(Pyrimidin-2-yl)cyclopropylamine; 1-(2-Pyrimidyl)cyclopropanamine; 1159878-06-4
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.