Description

2-(2-Cyanophenoxy)-4-Chloropyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine core functionalized with chlorophenoxy and cyano groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides with specific modes of action.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Material Science: Potential monomer or additive in the research of advanced polymers and functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and scale-up services.

Basic Information

Product Name	2-(2-Cyanophenoxy)-4-Chloropyrimidine
CAS No.	1159826-56-8
Molecular Formula	C11H6ClN3O
Molecular Weight	231.64 g/mol
Synonyms	4-Chloro-2-(2-cyanophenoxy)pyrimidine; 2-(4-Chloropyrimidin-2-yloxy)benzonitrile; 2-(2-Cyanophenoxy)-4-chloropyrimidine; 1159826-56-8; 4-Chloro-2-(2-cyanophenoxy)pyrimidine; 2-(4-Chloro-2-pyrimidinyloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-(2-Cyanophenoxy)-4-Chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.