Description

4-Chloro-2-(Piperidin-4-Yloxy)-Pyrimidine is a high-value pyrimidine derivative and a key synthetic intermediate in modern organic chemistry. This compound matters for its role as a versatile building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and cellular signaling processes.
• Material Science Research: Investigated as a monomer or functional unit in the design of advanced organic electronic materials and polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Utilized in university and government labs for methodological development and discovery chemistry.

Basic Information

Product Name	4-Chloro-2-(Piperidin-4-Yloxy)-Pyrimidine
CAS No.	1159823-41-2
Molecular Formula	C9H12ClN3O
Molecular Weight	213.66 g/mol
Synonyms	4-Chloro-2-(4-piperidinyloxy)pyrimidine; 2-(Piperidin-4-yloxy)-4-chloropyrimidine; 4-Chloro-2-(piperidin-4-yloxy)pyrimidine; Pyrimidine, 4-chloro-2-(4-piperidinyloxy)-; 1159823-41-2; 4-Chloro-2-(piperidin-4-yloxy)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Piperidin-4-Yloxy)-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.