Description

Ethyl 2-(7-Bromoquinazolin-2-Yl)Acetate is a high-value brominated quinazoline derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel pharmaceutical agents, particularly kinase inhibitors. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted therapeutic agents, especially protein kinase inhibitors for oncology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex quinazoline-based architectures in custom synthesis projects.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.

Basic Information

Product Name	Ethyl 2-(7-Bromoquinazolin-2-Yl)Acetate
CAS No.	1159812-67-5
Molecular Formula	C₁₂H₁₁BrN₂O₂
Molecular Weight	295.13 g/mol
Synonyms	Ethyl (7-bromoquinazolin-2-yl)acetate; 2-(7-Bromoquinazolin-2-yl)acetic acid ethyl ester; Ethyl 2-(7-bromo-2-quinazolinyl)acetate; 7-Bromo-2-quinazolineacetic acid ethyl ester; Acetic acid, 2-(7-bromoquinazolin-2-yl)-, ethyl ester; Ethyl (7-bromo-2-quinazolinyl)acetate; 1159812-67-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-(7-Bromoquinazolin-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.