Description

1-(Pyrimidin-2-Yl)Cyclopropan-1-Amine Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is valued for its unique cyclopropane-fused pyrimidine structure, which is a key motif in modern medicinal chemistry for developing novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs) and discovery of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel small molecule drugs targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex, biologically active molecules.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate for the development of new crop protection agents and pesticides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical development pipelines.

Basic Information

Product Name	1-(Pyrimidin-2-Yl)Cyclopropan-1-Amine Dihydrochloride
CAS No.	1159734-42-5
Molecular Formula	C7H12Cl2N3
Molecular Weight	209.10 g/mol
Synonyms	1-(Pyrimidin-2-yl)cyclopropanamine dihydrochloride; 1-(2-Pyrimidinyl)cyclopropanamine dihydrochloride; 1-Aminocyclopropylpyrimidine dihydrochloride; Cyclopropanamine, 1-(2-pyrimidinyl)-, dihydrochloride; 1-Cyclopropylaminopyrimidine dihydrochloride; 2-(1-Aminocyclopropyl)pyrimidine dihydrochloride; 1159734-42-5
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl)Cyclopropan-1-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.