Description

tert-Butyl n-[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a cyclopropyl ring fused with a pyrimidine heterocycle. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides that require specific heterocyclic frameworks for bioactivity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules for various high-value industrial applications.
• Academic & R&D Laboratories: Utilized in universities and corporate R&D centers for exploratory synthesis and methodological development.

Basic Information

Product Name	tert-Butyl n-[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamate
CAS No.	1159734-40-3
Molecular Formula	C₁₂H₁₇N₃O₂
Molecular Weight	235.28 g/mol
Synonyms	tert-Butyl N-[1-(pyrimidin-2-yl)cyclopropyl]carbamate; 1-(Pyrimidin-2-yl)cyclopropanamine, N-BOC-protected; BOC-1-(2-Pyrimidinyl)cyclopropylamine; Carbamic acid, N-[1-(2-pyrimidinyl)cyclopropyl]-, 1,1-dimethylethyl ester; 2-Pyrimidinecyclopropanamine, N-BOC derivative; 1,1-Dimethylethyl N-[1-(2-pyrimidinyl)cyclopropyl]carbamate; N-Boc-1-(pyrimidin-2-yl)cyclopropan-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[1-(Pyrimidin-2-Yl)Cyclopropyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.