Description

2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block, distinguished by its unique trifluoromethoxy and fluorine substituents. This compound matters for its critical role in facilitating the synthesis of complex molecules with enhanced metabolic stability, lipophilicity, and bioavailability. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups confer improved pest selectivity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to enhanced electronic properties and device performance.
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced resins that require specific dielectric properties or chemical resistance.
• Chemical Research & Development: Utilized as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up batch synthesis.

Basic Information

Item	Detail
Product Name	2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde
CAS No.	1159512-58-9
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2-Fluoro-3-(trifluoromethoxy)benzaldehyde; 3-Trifluoromethoxy-2-fluorobenzaldehyde; 2-Fluoro-α,α,α-trifluoro-m-anisaldehyde; Benzaldehyde, 2-fluoro-3-(trifluoromethoxy)-; 1159512-58-9
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.