Description

(4-Amino-3-Hydroxyphenyl)Sulfur Pentafluoride is a specialized organosulfur pentafluoride derivative that serves as a critical building block in advanced chemical synthesis. This compound matters for its unique combination of an aromatic amine, a phenol, and a highly reactive sulfur pentafluoride (SF5) group, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used to develop next-generation herbicides and pesticides with improved efficacy and environmental profiles by incorporating the metabolically stable SF5 moiety.
• Material Science: Serves as a monomer or cross-linking agent for creating high-performance polymers with enhanced thermal stability and chemical resistance.
• Ligand Synthesis: Building block for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorination Chemistry: Acts as a versatile reagent for introducing fluorine atoms and the SF5 group into organic molecules, a valuable transformation in medicinal chemistry.
• Dye & Pigment Development: Intermediate for synthesizing specialized dyes and functional pigments with unique optical properties.

Basic Information

Product Name	(4-Amino-3-Hydroxyphenyl)Sulfur Pentafluoride
CAS No.	1159512-48-7
Molecular Formula	C6H6F5NOS
Molecular Weight	235.18 g/mol
Synonyms	4-Amino-3-hydroxyphenylsulfur pentafluoride; 2-Amino-5-(pentafluoro-λ6-sulfanyl)phenol; 5-(Pentafluorosulfanyl)-2-aminophenol; SF5-Aniline Phenol Derivative; 1-Amino-2-hydroxy-4-(pentafluorosulfanyl)benzene; (4-Amino-3-hydroxy)phenyl SF5; Amino-hydroxy SF5 benzene
EINECS	Contact for details

Quality Control

Every batch of (4-Amino-3-Hydroxyphenyl)Sulfur Pentafluoride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.