Description

3-Bromo-4-Hydroxy-5-Nitrophenylsulphur Pentafluoride is a specialized organosulfur pentafluoride derivative, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its unique molecular structure, featuring bromo, hydroxy, and nitro substituents on a sulfur pentafluoride core, makes it a critical building block for introducing sulfur-fluorine motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring sulfur pentafluoride (SF5) bioisosteres for enhanced metabolic stability and lipophilicity.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the SF5 group can improve activity and environmental profile.
• Material Science: Building block for advanced polymers, liquid crystals, and electronic materials that benefit from the unique electronic properties of the SF5 moiety.
• Organic Synthesis Reagent: Serves as a versatile electrophile or coupling partner in cross-coupling reactions and nucleophilic aromatic substitution for introducing complex aromatic systems.
• Chemical Biology Probe Development: Utilized in creating labeled compounds and probes for studying biological mechanisms and protein interactions.

Basic Information

Product Name	3-Bromo-4-Hydroxy-5-Nitrophenylsulphur Pentafluoride
CAS No.	1159512-28-3
Molecular Formula	C6H3BrF5NO3S
Molecular Weight	328.06 g/mol
Synonyms	3-Bromo-4-hydroxy-5-nitrobenzenesulfonyl pentafluoride; (3-Bromo-4-hydroxy-5-nitrophenyl)sulfur pentafluoride; 1-Bromo-2-hydroxy-3-nitro-5-(pentafluoro-λ6-sulfanyl)benzene; SF5-Aromatic Intermediate; Pentafluorosulfur Benzene Derivative
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-4-Hydroxy-5-Nitrophenylsulphur Pentafluoride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and meet the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.