Description

5-Chlorosulfonyl-2-Fluoro-Benzoic Acid Ethyl Ester is a high-value, multi-functional chemical intermediate prized for its reactive chlorosulfonyl and ester groups. This compound is essential for the synthesis of complex molecules, enabling the introduction of key functional handles for further derivatization. It is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and fluorine-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom and sulfonyl chloride moiety enhance biological activity and stability.
• Material Science Research: Serves as a precursor for creating specialized polymers, liquid crystals, and organic electronic materials that require specific sulfonyl and fluorinated aromatic units.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring complex, multi-step organic synthesis.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in research tools and diagnostic agent development.

Basic Information

Product Name	5-Chlorosulfonyl-2-Fluoro-Benzoic Acid Ethyl Ester
CAS No.	1155985-73-1
Molecular Formula	C9H8ClFO4S
Molecular Weight	266.67 g/mol
Synonyms	Ethyl 5-(Chlorosulfonyl)-2-fluorobenzoate; 2-Fluoro-5-(chlorosulfonyl)benzoic Acid Ethyl Ester; Benzoic acid, 5-(chlorosulfonyl)-2-fluoro-, ethyl ester; Ethyl 2-fluoro-5-(chlorosulfonyl)benzoate; 5-Chlorosulfonyl-2-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Chlorosulfonyl-2-Fluoro-Benzoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.