Description

Ethyl2-Chloro-5-(Chlorosulfonyl)-4-Fluorobenzoate is a high-value, multi-functional aromatic ester and sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an activated ester and a reactive chlorosulfonyl group, makes it indispensable for the precise construction of complex molecules. This intermediate is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the benzoate and sulfonyl chloride functionalities are leveraged for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Utilized as a reactive probe or labeling reagent for modifying proteins and studying biological pathways due to its electrophilic chlorosulfonyl group.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex chromophores and specialty colorants.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl2-Chloro-5-(Chlorosulfonyl)-4-Fluorobenzoate
CAS No.	1155076-35-9
Molecular Formula	C9H7Cl2FO4S
Molecular Weight	305.12 g/mol
Synonyms	Ethyl 2-Chloro-5-(chlorosulfonyl)-4-fluorobenzoate; 4-Fluoro-2-chloro-5-(chlorosulfonyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-chloro-5-(chlorosulfonyl)-4-fluoro-, ethyl ester; Ethyl 4-fluoro-2-chloro-5-(chlorosulfonyl)benzoate
EINECS	Contact for details

Quality Control

Our production of Ethyl2-Chloro-5-(Chlorosulfonyl)-4-Fluorobenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.