Description

1-[4-Amino-3-(Trifluoromethyl)Phenyl]-N,n-Dimethylpiperidin-4-Amine is a high-value, multifunctional organic intermediate featuring a trifluoromethylphenyl and a dimethylpiperidinylamine scaffold. This compound matters for its unique structural properties, which are critical for modulating the biological activity and physicochemical characteristics of advanced molecules. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring specific amine functionalities.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for catalytic systems and metal-organic frameworks (MOFs).
• Fluorinated Compound Libraries: An essential component for constructing diverse screening libraries in medicinal chemistry for hit identification.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.

Basic Information

Item	Details
Product Name	1-[4-Amino-3-(Trifluoromethyl)Phenyl]-N,n-Dimethylpiperidin-4-Amine
CAS No.	1154664-52-4
Molecular Formula	C14H20F3N3
Molecular Weight	287.33 g/mol
Synonyms	4-(4-Amino-3-(trifluoromethyl)phenyl)-N,N-dimethylpiperidin-4-amine; 1-[4-Amino-3-(trifluoromethyl)phenyl]-N,N-dimethyl-4-piperidinamine; N,N-Dimethyl-1-[4-amino-3-(trifluoromethyl)phenyl]piperidin-4-amine; 1154664-52-4; 4-Piperidinamine, 1-[4-amino-3-(trifluoromethyl)phenyl]-N,N-dimethyl-; 1-(4-Amino-3-trifluoromethylphenyl)-N,N-dimethylpiperidin-4-amine
EINECS	Contact for details

Quality Control

Our 1-[4-Amino-3-(Trifluoromethyl)Phenyl]-N,n-Dimethylpiperidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.