Description

(3-Chloro-5-(Trifluoromethyl)Phenyl)Methanesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the (3-chloro-5-(trifluoromethyl)phenyl)methanesulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and sulfonyl groups.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced materials with unique surface properties.
• Chemical Research: A versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and pigments requiring sulfonated structures for solubility and color fastness.

Basic Information

Product Name	(3-Chloro-5-(Trifluoromethyl)Phenyl)Methanesulfonyl Chloride
CAS No.	1154614-69-3
Molecular Formula	C9H5Cl2F3O2S
Molecular Weight	313.10 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)benzenemethanesulfonyl chloride; 1-Chloro-3-(chloromethylsulfonyl)-5-(trifluoromethyl)benzene; (3-Chloro-5-(trifluoromethyl)phenyl)methanesulfonyl chloride; α-Chloro-3-chloro-5-(trifluoromethyl)benzenemethanesulfonate; Benzenemethanesulfonyl chloride, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-α,α,α-trifluoro-5-(chlorosulfonylmethyl)toluene
EINECS	Contact for details

Quality Control

Our production of (3-Chloro-5-(Trifluoromethyl)Phenyl)Methanesulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.