Description

Methyl 2-(6-Amino-4-Oxo-3,4-Dihydroquinazolin-3-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its quinazolinone core structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition and other enzymatic pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel chemical libraries for high-throughput screening.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays to study protein-ligand interactions and cellular signaling mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	Methyl 2-(6-Amino-4-Oxo-3,4-Dihydroquinazolin-3-Yl)Acetate
CAS No.	1154233-36-9
Molecular Formula	C11H11N3O3
Molecular Weight	233.22 g/mol
Synonyms	Methyl (6-Amino-4-oxo-3,4-dihydroquinazolin-3-yl)acetate; 3-Quinazolinoneacetic acid, 6-amino-3,4-dihydro-4-oxo-, methyl ester; Methyl 2-(6-amino-4-oxo-3,4-dihydroquinazolin-3-yl)ethanoate; 6-Amino-3-(carboxymethyl)-4(3H)-quinazolinone methyl ester; 1154233-36-9
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(6-Amino-4-Oxo-3,4-Dihydroquinazolin-3-Yl)Acetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.