Description

(2-Methylpyrimidin-4-Yl)Methylamine Dihydrochloride CAS NO 1153235-58-5 is a high-purity, organically synthesized chemical building block primarily used in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. Its primary value lies in enabling medicinal chemists to explore new molecular entities with potential biological activity. Key industries that utilize this material include pharmaceutical R&D, contract research organizations (CROs), and fine chemical manufacturers focused on producing specialized intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce the (2-methylpyrimidin-4-yl)methylamine moiety into new chemical entities.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study biological pathways and protein function.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and herbicides.
• Material Science Research: Can be utilized in the development of organic ligands for catalysts or advanced functional materials.

Basic Information

Product Name	(2-Methylpyrimidin-4-Yl)Methylamine Dihydrochloride
CAS No.	1153235-58-5
Molecular Formula	C6H10N3·2HCl
Molecular Weight	197.09 g/mol (Free base: 124.16 g/mol)
Synonyms	4-(Aminomethyl)-2-methylpyrimidine dihydrochloride; 2-Methyl-4-(aminomethyl)pyrimidine dihydrochloride; 1-(2-Methylpyrimidin-4-yl)methanamine dihydrochloride; (2-Methyl-4-pyrimidinyl)methylamine dihydrochloride; 4-(Aminomethyl)-2-methylpyrimidine hydrochloride (1:2); (2-Methylpyrimidin-4-yl)methanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (2-Methylpyrimidin-4-Yl)Methylamine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.