Description

n-Ethyl-2,3-Difluorobenzylamine is a high-purity, fluorinated benzylamine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the introduction of both fluorine atoms and a functionalized amine group into complex molecular architectures. Pharmaceutical, agrochemical, and material science researchers need it for developing new active ingredients and specialty chemicals with tailored properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorobenzyl moiety enhances bioavailability and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science: Building block for specialty polymers, liquid crystals, and organic electronic materials where fluorine substitution modifies electronic properties and stability.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	n-Ethyl-2,3-Difluorobenzylamine
CAS No.	1152832-76-2
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	2,3-Difluoro-N-ethylbenzylamine; 1-(2,3-Difluorophenyl)-N-ethylmethanamine; N-Ethyl(2,3-difluorophenyl)methanamine; (2,3-Difluorobenzyl)ethylamine; Benzylamine, 2,3-difluoro-N-ethyl-; N-Ethyl-2,3-difluorobenzylamine; Ethyl(2,3-difluorobenzyl)amine
EINECS	Contact for details

Quality Control

Our n-Ethyl-2,3-Difluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This amine derivative is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere such as nitrogen after opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Density	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.