Description

4,6-Dichloro-2-Ethyl-5-Fluoropyrimidine is a high-value fluorinated pyrimidine building block, a key intermediate in modern synthetic chemistry. Its molecular structure, featuring reactive chlorine and fluorine substituents, makes it indispensable for constructing complex molecules with precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its fluorinated pyrimidine core.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and advanced polymeric materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitution reactions to introduce the 2-ethyl-5-fluoro-pyrimidine moiety into target molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.

Basic Information

Product Name	4,6-Dichloro-2-Ethyl-5-Fluoropyrimidine
CAS No.	1152109-89-1
Molecular Formula	C6H5Cl2FN2
Molecular Weight	195.02 g/mol
Synonyms	2-Ethyl-4,6-dichloro-5-fluoropyrimidine; 5-Fluoro-4,6-dichloro-2-ethylpyrimidine; 4,6-Dichloro-5-fluoro-2-ethylpyrimidine; 2-Ethyl-5-fluoro-4,6-dichloropyrimidine; DC2E5FP; Pyrimidine, 4,6-dichloro-2-ethyl-5-fluoro-
EINECS	Contact for details

Quality Control

Our production of 4,6-Dichloro-2-Ethyl-5-Fluoropyrimidine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.