Description

2,4-Dichloro-Quinazoline-8-Carbonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazoline scaffold, functionalized with reactive chloro and cyano groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Dichloro-Quinazoline-8-Carbonitrile
CAS No.	1150617-71-2
Molecular Formula	C9H3Cl2N3
Molecular Weight	224.05 g/mol
Synonyms	8-Cyano-2,4-dichloroquinazoline; 2,4-Dichloro-8-cyanoquinazoline; Quinazoline-8-carbonitrile, 2,4-dichloro-; 2,4-Dichloroquinazoline-8-carbonitrile; 1150617-71-2
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-Quinazoline-8-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.