Description

2,5-Difluoro-4-Thiocyanatoaniline,Hcl is a specialized aromatic amine derivative that serves as a high-value building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining fluorine and thiocyanate functional groups to impart specific reactivity and physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides where the difluoro and thiocyanate groups enhance biological activity.
• Material Science: Serves as a monomer or precursor for specialty polymers and functional materials requiring specific surface properties.
• Ligand Synthesis: Useful in organometallic chemistry for creating novel ligands in catalytic systems.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and colorants.
• Cross-coupling Reactions: Acts as a substrate in Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to construct complex molecules.

Basic Information

Product Name	2,5-Difluoro-4-Thiocyanatoaniline,Hcl
CAS No.	1150114-25-2
Molecular Formula	C7H5ClF2N2S
Molecular Weight	222.64 g/mol
Synonyms	4-Amino-2,5-difluorophenyl thiocyanate hydrochloride; 2,5-Difluoro-4-thiocyanatoaniline hydrochloride; 4-Thiocyanato-2,5-difluoroaniline HCl; Benzenamine, 2,5-difluoro-4-thiocyanato-, hydrochloride; 2,5-Difluoro-4-isothiocyanatoaniline hydrochloride (tautomeric form); 1150114-25-2; 2,5-DFTA HCl
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Thiocyanatoaniline,Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.