Description

3-Chloro-4-(6-Chloro-5-Fluoropyrimidin-4-Ylamino)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyrimidine and benzonitrile structure. This compound is critical for the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, especially kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its pyrimidine-based scaffold.
• Antiviral Agent Development: Serves as a precursor in the research of antiviral compounds.
• Agrochemical Synthesis: Potential intermediate for creating advanced herbicides or fungicides.
• Chemical Biology: Employed in probe and tool compound development for studying biological pathways.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.

Basic Information

Item	Detail
Product Name	3-Chloro-4-(6-Chloro-5-Fluoropyrimidin-4-Ylamino)Benzonitrile
CAS No.	1147558-27-7
Molecular Formula	C11H5Cl2FN4
Molecular Weight	283.09 g/mol
Synonyms	3-Chloro-4-[(6-chloro-5-fluoropyrimidin-4-yl)amino]benzonitrile; 4-Amino-3-chlorobenzonitrile, 6-chloro-5-fluoro-pyrimidin-4-yl deriv.; 1147558-27-7; 3-Chloro-4-((6-chloro-5-fluoropyrimidin-4-yl)amino)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(6-Chloro-5-Fluoropyrimidin-4-Ylamino)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support development and commercial projects with material suitable for GMP synthesis upon agreement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.