Description

2,5-Difluoro-4-(Methylsulfonyl)Aniline is a high-purity, multi-functional aniline derivative characterized by its difluoro and methylsulfonyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in the synthesis of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the difluoro and sulfonyl motifs.
• Material Science: Used in the research and production of advanced polymers, liquid crystals, and electronic materials where specific fluorine-containing aromatic structures are required.
• Organic Synthesis & Research: A valuable reagent for Suzuki-Miyaura and other cross-coupling reactions, as well as for introducing sulfonamide functionalities into target molecules in medicinal chemistry.
• Dye & Pigment Industry: Intermediate for manufacturing specialized dyes and pigments that require high lightfastness and chemical stability.

Basic Information

Product Name	2,5-Difluoro-4-(Methylsulfonyl)Aniline
CAS No.	1147557-75-2
Molecular Formula	C7H7F2NO2S
Molecular Weight	207.20 g/mol
Synonyms	4-Amino-2,5-difluorophenyl methyl sulfone; 2,5-Difluoro-4-(methylsulfonyl)benzenamine; 4-(Methylsulfonyl)-2,5-difluoroaniline; Benzenamine, 2,5-difluoro-4-(methylsulfonyl)-; 2,5-Difluoro-4-methylsulfonylaniline
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-(Methylsulfonyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP and ISO 9001 standards to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.