Description

2,6-Difluoro-4-(Methylsulfonyl)Aniline is a high-purity, multi-functional aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing sulfonyl and fluorine substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro-aniline core contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional dyes, pigments, and advanced polymers where sulfonyl and fluorine groups modify electronic properties and durability.
• Ligand and Catalyst Development: Employed in organic chemistry research to create novel ligands for metal catalysis and asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	2,6-Difluoro-4-(Methylsulfonyl)Aniline
CAS No.	1147557-74-1
Molecular Formula	C7H7F2NO2S
Molecular Weight	207.20 g/mol
Synonyms	4-Amino-3,5-difluorophenyl methyl sulfone; 2,6-Difluoro-4-(methylsulfonyl)benzenamine; 3,5-Difluoro-4-aminophenyl methyl sulfone; Benzenamine, 2,6-difluoro-4-(methylsulfonyl)-; 4-(Methylsulfonyl)-2,6-difluoroaniline; 2,6-Difluoro-4-methanesulfonylaniline
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-(Methylsulfonyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.