Description

2-Fluoropropane-1-Sulfonyl Chloride is a specialized organofluorine building block and sulfonylating agent of significant interest in advanced chemical synthesis. Its core value lies in its ability to introduce the 2-fluoropropanesulfonyl moiety, a key functional group for modulating the physicochemical and biological properties of target molecules. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs and protease inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a precursor for modifying polymer surfaces and creating specialty materials with specific surface properties.
• Chemical Research & Development: A versatile reagent in organic synthesis for introducing fluorinated sulfonyl groups, enabling structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Fluoropropane-1-Sulfonyl Chloride
CAS No.	1146664-21-2
Molecular Formula	C3H6ClFO2S
Molecular Weight	156.59 g/mol
Synonyms	1-Fluoro-2-propanesulfonyl chloride; 2-Fluoropropanesulfonyl chloride; 2-Fluoropropylsulfonyl chloride; 1-Fluoropropane-2-sulfonyl chloride; Propane-1-sulfonyl chloride, 2-fluoro-; 2-FPS-Cl
EINECS	Contact for details

Quality Control

Our 2-Fluoropropane-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.