Description

2-(2-Bromo-Pyridin-3-Yloxy)-Pyrimidine is a high-purity (98+%) heterocyclic organic compound with the molecular formula C9H6BrN3O and a molecular weight of 252.07. This brominated pyridine-pyrimidine derivative is a critical pharmaceutical intermediate and building block for advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a versatile building block for developing novel herbicides, fungicides, and insecticides.
• Material Science Research: Used in the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), and functional polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(2-Bromo-Pyridin-3-Yloxy)-Pyrimidine
CAS No.	1146080-79-6
Molecular Formula	C9H6BrN3O
Molecular Weight	252.07 g/mol
Synonyms	2-(2-Bromopyridin-3-yloxy)pyrimidine; 3-(Pyrimidin-2-yloxy)-2-bromopyridine; Pyrimidine, 2-[(2-bromo-3-pyridinyl)oxy]-; 2-Bromo-3-(pyrimidin-2-yloxy)pyridine; 2-(2-Bromo-3-pyridyloxy)pyrimidine; 1146080-79-6
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-Pyridin-3-Yloxy)-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure the specified purity of 98+% and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.