Description

3-(6-Chloro-Pyrimidin-4-Yl)-1H-Indole is a high-purity (98+%) heterocyclic organic compound with the molecular formula C12H8ClN3 and a molecular weight of 229.67. This versatile indole-pyrimidine hybrid serves as a critical advanced pharmaceutical intermediate and a valuable scaffold for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and development of new herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Organic Synthesis: Acts as a versatile reactant for constructing complex heterocyclic systems through cross-coupling and other advanced reactions.

Basic Information

Product Name	3-(6-Chloro-Pyrimidin-4-Yl)-1H-Indole
CAS No.	1146080-38-7
Molecular Formula	C12H8ClN3
Molecular Weight	229.67 g/mol
Synonyms	3-(6-Chloropyrimidin-4-yl)-1H-indole; 1H-Indole, 3-(6-chloro-4-pyrimidinyl)-; 3-(6-Chloro-4-pyrimidinyl)indole; 6-Chloro-4-(1H-indol-3-yl)pyrimidine; 4-(1H-Indol-3-yl)-6-chloropyrimidine; 3-(6-Chloro-4-pyrimidyl)indole; 3-(6-Chloro-pyrimidin-4-yl)-indole
EINECS	Contact for details

Quality Control

Our 3-(6-Chloro-Pyrimidin-4-Yl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the purity exceeds 98% and meets the stringent requirements for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.