Description

4-Chloro-6-(1-Pyrazin-2-Yl-Ethoxy)-Pyrimidine is a high-purity (98+%) heterocyclic organic compound with the molecular formula C10H9ClN4O and a molecular weight of 236.66. This specialized pyrimidine derivative serves as a critical pharmaceutical intermediate and building block in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides or fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic and organic chemistry.

Basic Information

Product Name	4-Chloro-6-(1-Pyrazin-2-Yl-Ethoxy)-Pyrimidine
CAS No.	1146080-25-2
Molecular Formula	C10H9ClN4O
Molecular Weight	236.66 g/mol
Synonyms	4-Chloro-6-[(1-pyrazin-2-yl)ethoxy]pyrimidine; 4-Chloro-6-(pyrazin-2-ylethoxy)pyrimidine; 4-Chloro-6-(1-(pyrazin-2-yl)ethoxy)pyrimidine; 6-(1-Pyrazin-2-ylethoxy)-4-chloropyrimidine; 4-Chloro-6-(2-pyrazin-2-ylethoxy)pyrimidine; Pyrimidine, 4-chloro-6-[(1-pyrazin-2-yl)ethoxy]-; 1146080-25-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(1-Pyrazin-2-Yl-Ethoxy)-Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.