Description

2-{[(2-Aminoethyl)Thio]Methyl}-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure containing fused pyrimidine and thiophene rings. This compound is of significant commercial value for its role as a key building block in the synthesis of novel, potent therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors and other targeted therapies.
• Oncology Research: Serves as a core scaffold for developing novel anti-cancer compounds due to its privileged structure that can interact with specific biological targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes to enhance drug potency, selectivity, and pharmacokinetic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme function and cellular signaling pathways.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	2-{[(2-Aminoethyl)Thio]Methyl}-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One
CAS No.	1144461-80-2
Molecular Formula	C12H15N3OS2
Molecular Weight	281.40 g/mol
Synonyms	2-[(2-Aminoethylthio)methyl]-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one; 2-{[(2-Aminoethyl)sulfanyl]methyl}-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one; CAS 1144461-80-2; Cyclopentathienopyrimidinone derivative; Aminoethylthio-methyl thienopyrimidinone.
EINECS	Contact for details

Quality Control

Our 2-{[(2-Aminoethyl)Thio]Methyl}-3,5,6,7-Tetrahydro-4H-Cyclopenta[4,5]Thieno[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.