Description

3-(6-Chloro-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)-8-Oxa-3-Azabicyclo[3.2.1]Octane is a sophisticated heterocyclic organic compound featuring a complex fused ring system. This high-value intermediate is critical for pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, drug-like scaffold.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Probe Synthesis: Utilized to create tool compounds for investigating specific biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.
• Academic Research: Used in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(6-Chloro-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)-8-Oxa-3-Azabicyclo[3.2.1]Octane
CAS No.	1144080-35-2
Molecular Formula	C22H27ClN6O3
Molecular Weight	458.94 g/mol
Synonyms	8-Oxa-3-azabicyclo[3.2.1]octane, 3-[6-chloro-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-; 1144080-35-2; 3-(6-Chloro-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane; 8-Oxa-3-azabicyclo[3.2.1]octane, 3-(6-chloro-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-; Bicyclo[3.2.1]octane-3-carboxamide derivative; Pyrazolopyrimidine spiroketal intermediate
EINECS	Contact for details

Quality Control

Our 3-(6-Chloro-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)-8-Oxa-3-Azabicyclo[3.2.1]Octane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality management standards, and specifications can be developed to meet the requirements of GMP or other regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.