Description

Urea, n-[4-(4-Methyl-1-Piperazinyl)Phenyl]-N'-[4-[4-(8-Oxa-3-Azabicyclo[3.2.1]Oct-3-Yl)-1-(2,2,2-Trifluoroethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl]Phenyl]- is a sophisticated, high-purity chemical building block designed for advanced research and development. This compound is critical for medicinal chemistry programs, particularly in the discovery and optimization of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold or building block in structure-activity relationship (SAR) studies and lead optimization campaigns.
• Biochemical Probe Development: Employed in the synthesis of tool compounds for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug discovery projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Item	Details
Product Name	Urea, n-[4-(4-Methyl-1-Piperazinyl)Phenyl]-N'-[4-[4-(8-Oxa-3-Azabicyclo[3.2.1]Oct-3-Yl)-1-(2,2,2-Trifluoroethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl]Phenyl]-
CAS No.	1144072-40-1
Molecular Formula	C32H35F3N8O2
Molecular Weight	620.67 g/mol
Synonyms	N-[4-(4-Methylpiperazin-1-yl)phenyl]-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]urea; 1144072-40-1; UNII-3F2Q2P3U7W; 3F2Q2P3U7W; BDBM50157863; CHEMBL3186662; AKOS025147065; ZINC000003869007
EINECS	Contact for details

Quality Control

Our Urea, n-[4-(4-Methyl-1-Piperazinyl)Phenyl]-N'-[4-[4-(8-Oxa-3-Azabicyclo[3.2.1]Oct-3-Yl)-1-(2,2,2-Trifluoroethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.