Description

4-(4-(8-Oxa-3-Azabicyclo[3.2.1]Octan-3-Yl)-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small molecule drugs targeting specific kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for oncology and other therapeutic areas.
• Biochemical Tool Compound: Serves as a precursor for developing selective enzyme inhibitors used in biological pathway studies.
• Preclinical Drug Development: Essential for producing candidate compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: Basis for contract research organizations (CROs) and CDMOs to produce bespoke molecules for client projects.
• Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and drug discovery programs.

Basic Information

Product Name	4-(4-(8-Oxa-3-Azabicyclo[3.2.1]Octan-3-Yl)-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Aniline
CAS No.	1144068-84-7
Molecular Formula	C26H33N7O3
Molecular Weight	491.59 g/mol
Synonyms	4-[4-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]aniline; 4-(4-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)benzenamine; Aniline, 4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1-(1,4-dioxaspiro[4.5]dec-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-; CAS 1144068-84-7; 1144068-84-7; 4-(4-(8-Oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenylamine
EINECS	Contact for details

Quality Control

Our 4-(4-(8-Oxa-3-Azabicyclo[3.2.1]Octan-3-Yl)-1-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric oxygen. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.