Description

3-(Aminomethyl)-2-Fluorophenol Hydrobromide is a specialized fluorinated phenolic compound with an aminomethyl side chain, offered as its hydrobromide salt for enhanced stability and handling. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate a unique fluorophenol scaffold into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to the fluorophenol moiety.
• Agrochemical Research: Used in developing new herbicides, fungicides, and pesticides where the fluorine atom and phenolic group can enhance biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The structural motif is valuable for constructing advanced organic fluorophores and molecular probes for bioimaging and diagnostics.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing fluorine and phenolic groups into specialty polymers to alter surface properties and reactivity.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology studies in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-(Aminomethyl)-2-Fluorophenol Hydrobromide
CAS No.	1143571-75-8
Molecular Formula	C7H9FNO•HBr
Molecular Weight	220.06 g/mol (Free base: 141.15 g/mol)
Synonyms	2-Fluoro-3-(aminomethyl)phenol hydrobromide; 3-(Aminomethyl)-2-fluorophenol HBr; (3-Amino-6-fluorobenzyl) alcohol hydrobromide (tautomeric form); 2-Fluoro-3-hydroxybenzylamine hydrobromide; 3-Hydroxy-2-fluorobenzylamine hydrobromide; 2-Fluoro-3-(hydroxymethyl)aniline hydrobromide; FAMP-HBr; CAS 1143571-75-8
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)-2-Fluorophenol Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data for identity, purity, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.