Description

3-Bromo-4,5-Difluorobenzyl Alcohol is a high-value, multi-functional aromatic building block characterized by its bromine and fluorine substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the difluoro and bromo groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for advanced electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The benzyl bromide derivative (easily accessed from this alcohol) is a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Ligand & Catalyst Development: Utilized in the preparation of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Polymer Modification: Incorporated as a monomer or modifier to impart unique solubility, thermal stability, or optical properties to high-performance engineering plastics.

Basic Information

Product Name	3-Bromo-4,5-Difluorobenzyl Alcohol
CAS No.	1143502-71-9
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(3-Bromo-4,5-difluorophenyl)methanol; 4,5-Difluoro-3-bromobenzyl Alcohol; 1-(Bromomethyl)-2,3-difluoro-4-bromobenzene (incorrect but common misnomer); 3-Bromo-4,5-difluorobenzenemethanol; Benzyl alcohol, 3-bromo-4,5-difluoro-; AI3-73600; ZINC000103014757
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4,5-Difluorobenzyl Alcohol is manufactured and analyzed under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard quality control protocols are designed to meet the stringent requirements of research and scale-up processes, ensuring batch-to-batch consistency and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.