Description

7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine, 4-Chloro-n-[4-(4-Methyl-1-Piperazinyl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate belonging to the heterocyclic pyrrolopyrimidine class. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for oncology and other therapeutic areas.
• Kinase Inhibitor Research: Serves as a core scaffold for the design and development of novel protein kinase inhibitors, targeting specific signaling pathways.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Biochemical Research: Employed as a reference standard or a tool compound in biochemical and pharmacological assays.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine, 4-Chloro-n-[4-(4-Methyl-1-Piperazinyl)Phenyl]-
CAS No.	1142946-17-5
Molecular Formula	C17H20ClN7
Molecular Weight	357.84 g/mol
Synonyms	4-Chloro-N-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidine; UNII-1Q6E8V8C8F; 1Q6E8V8C8F; 1142946-17-5; 4-Chloro-N-(4-(4-methyl-1-piperazinyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Chloro-N-[4-(4-methyl-1-piperazinyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine, 4-Chloro-n-[4-(4-Methyl-1-Piperazinyl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.