Description

4H-Pyrrolo[2,3-D]Pyrimidin-4-One, 3,7-Dihydro-2-[[4-(4-Methyl-1-Piperazinyl)Phenyl]Amino]- is a high-purity heterocyclic organic compound serving as a critical building block in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which makes it a key intermediate in the synthesis of targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery of novel small-molecule drugs, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and biological pathway studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	4H-Pyrrolo[2,3-D]Pyrimidin-4-One, 3,7-Dihydro-2-[[4-(4-Methyl-1-Piperazinyl)Phenyl]Amino]-
CAS No.	1142946-16-4
Molecular Formula	C17H20N6O
Molecular Weight	324.38 g/mol
Synonyms	2-[[4-(4-Methylpiperazin-1-yl)phenyl]amino]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; UNII-8V0N1B717N; 8V0N1B717N; 2-({4-[4-Methylpiperazin-1-yl]phenyl}amino)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; 2-((4-(4-Methylpiperazin-1-yl)phenyl)amino)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; BDBM50164957; HY-101966; CS-0105597; AKOS025147064
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality assurance is conducted in compliance with cGMP guidelines where applicable, utilizing advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.