Description

7H-Pyrrolo[2,3-D]Pyrimidine, 2-Chloro-7-[(4-Methylphenyl)Sulfonyl]-4-(4-Methyl-2-Thienyl)- is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study specific biological pathways and enzyme inhibition mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic molecules for advanced material science.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidine, 2-Chloro-7-[(4-Methylphenyl)Sulfonyl]-4-(4-Methyl-2-Thienyl)-
CAS No.	1142945-86-5
Molecular Formula	C18H15ClN2O2S2
Molecular Weight	398.91 g/mol
Synonyms	2-Chloro-7-[(4-methylphenyl)sulfonyl]-4-(4-methyl-2-thienyl)-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-4-(4-methylthiophen-2-yl)-7-(p-tolylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; 1142945-86-5; 7H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-7-[(4-methylphenyl)sulfonyl]-4-(4-methyl-2-thienyl)-; Pyrrolopyrimidine sulfonamide derivative; Kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Every batch of our 7H-Pyrrolo[2,3-D]Pyrimidine intermediate undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the stringent requirements of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation (IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.