Description

4H-Pyrrolo[2,3-D]Pyrimidin-4-One, 3,7-Dihydro-2-[[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]- is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This heterocyclic compound serves as a critical building block for the synthesis of novel kinase inhibitors and targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of oncology and anti-inflammatory treatments, where precise molecular structure and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small molecule kinase inhibitors for oncology research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Serves as a reference standard or probe compound in enzymatic assays and target validation studies.
• API Synthesis: Employed in the scalable production route development for potential Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: Starting material for the preparation of more complex, proprietary analogs in contract research organizations (CROs).

Basic Information

Product Name	4H-Pyrrolo[2,3-D]Pyrimidin-4-One, 3,7-Dihydro-2-[[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]-
CAS No.	1142945-82-1
Molecular Formula	C18H21N5O2
Molecular Weight	339.39 g/mol
Synonyms	2-((4-(2-(Pyrrolidin-1-yl)ethoxy)phenyl)amino)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; UNII-7V4A8U16JN; 7V4A8U16JN; BDBM50190057; AKOS025310994; CS-0335379; FT-0775687; NS-01479; AOB83707
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.