Description

4-Bromo-2-(tert-Butyl)Pyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a bromine substituent and a bulky tert-butyl group, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and plant growth regulators, leveraging its pyrimidine core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science: Building block for organic electronic materials, such as OLEDs and semiconductors, where its structure can modify electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to specialized chemical needs.

Basic Information

Product Name	4-Bromo-2-(tert-Butyl)Pyrimidine
CAS No.	1142195-70-7
Molecular Formula	C8H11BrN2
Molecular Weight	215.09 g/mol
Synonyms	2-tert-Butyl-4-bromopyrimidine; 4-Bromo-2-tert-butylpyrimidine; Pyrimidine, 4-bromo-2-(1,1-dimethylethyl)-; 4-Bromo-2-(1,1-dimethylethyl)pyrimidine; 4-Bromo-2-(tert-butyl)pyrimidine; 2-(tert-Butyl)-4-bromopyrimidine; 4-Bromo-2-t-butylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(tert-Butyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in GLP and cGMP environments where traceability and documentation are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.