Description

Gastric Inhibitory Polypeptide (6-30) Amide (Human) is a synthetic peptide fragment corresponding to the 6-30 sequence of the human Gastric Inhibitory Polypeptide (GIP), modified with a C-terminal amide group. This compound is a crucial research tool for investigating the structure-activity relationships, receptor binding, and metabolic functions of GIP, a key incretin hormone involved in glucose homeostasis. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, diabetes research, and metabolic disorder therapeutics.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of GIP receptor (GIPR) signaling and pharmacology.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel GIP-based therapeutics for Type 2 diabetes and obesity.
• Assay Development: Employed in the development and validation of immunoassays (ELISA, RIA) and cell-based bioassays to quantify GIP activity.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping the bioactive regions of the full-length GIP hormone to design more stable and potent analogs.
• Academic & Clinical Studies: Supports fundamental research into the role of GIP in insulin secretion, fat metabolism, and bone biology.

Basic Information

Item	Detail
Product Name	Gastric Inhibitory Polypeptide (6-30) Amide (Human)
CAS No.	1139691-72-7
Molecular Formula	C124H204N38O39
Molecular Weight	2795.2 g/mol (theoretical)
Synonyms	GIP (6-30) amide, human; Glucose-dependent Insulinotropic Polypeptide (6-30) amide; GIP fragment 6-30 amide; Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-NH2 (Sequence); Synthetic GIP amide fragment
EINECS	Contact for details

Quality Control

Our Gastric Inhibitory Polypeptide (6-30) Amide (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.