Description

2-Pyrimidinamine, 4-[5-(3,5-Dimethyl-4-Isoxazolyl)-2-Thienyl]-5-Methyl-n-[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of investigational new drugs, particularly in oncology and other therapeutic areas.
• Biochemical Research: Used as a reference standard or a molecular probe in pharmacological and biological studies to investigate structure-activity relationships (SAR).
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct sophisticated heterocyclic frameworks.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Academic Research: Utilized in university and institutional laboratories for advanced chemical research and methodology development.

Basic Information

Product Name	2-Pyrimidinamine, 4-[5-(3,5-Dimethyl-4-Isoxazolyl)-2-Thienyl]-5-Methyl-n-[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]-
CAS No.	1138472-98-6
Molecular Formula	C26H29N5O2S
Molecular Weight	475.61 g/mol
Synonyms	4-[5-(3,5-Dimethylisoxazol-4-yl)thiophen-2-yl]-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrimidin-2-amine; GSK-3 Inhibitor XV; CAS 1138472-98-6; 2-Amino-4-[5-(3,5-dimethyl-4-isoxazolyl)-2-thienyl]-5-methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]pyrimidine; GSK-3β Inhibitor XV; 6H-Purin-6-one, 1,9-dihydro-; (Research Code Compound)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation, ensuring it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.