Description

Neuromedin S (Human) is a bioactive neuropeptide belonging to the neuromedin family, identified as a potent endogenous ligand for the neuromedin U receptor 2 (NMUR2). This compound plays a significant role in regulating diverse physiological processes, including energy homeostasis, circadian rhythms, and stress responses. It is a critical research tool for neuroscientists, pharmacologists, and drug discovery teams in the pharmaceutical and biotechnology sectors, particularly for studying neuroendocrine signaling and developing novel therapeutic agents for metabolic and neurological disorders. CAS No. 1138204-27-9.

Application

• Neuroscience Research: Fundamental studies on neuropeptide signaling, receptor binding affinity (NMUR2), and neuronal circuit function.
• Drug Discovery & Development: High-throughput screening for receptor agonists/antagonists and lead compound optimization for metabolic and CNS disorders.
• Metabolic Disorder Studies: Investigation of its role in appetite regulation, energy expenditure, and body weight control for obesity and diabetes research.
• Circadian Biology: Research into its function as a circadian output signal from the suprachiasmatic nucleus (SCN).
• Biochemical Assay Standard: Use as a reference standard in ELISA, RIA, and functional cell-based assays to ensure data accuracy and reproducibility.
• Academic & Institutional Research: A key reagent for university and research institute labs focusing on neuroendocrinology and peptide pharmacology.

Basic Information

Product Name	Neuromedin S (Human)
CAS No.	1138204-27-9
Molecular Formula	C85H138N26O26S2
Molecular Weight	1936.3 g/mol
Synonyms	Neuromedin-S; NMS; hNMS; TAN-112; Neuromedin S Precursor; Neuromedin S (1-33); Neuromedin S, human; NmS; NM-S; Neuromedin U receptor 2 ligand
EINECS	Contact for details

Quality Control

Our Neuromedin S (Human) is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results and guaranteeing traceability and batch-to-batch consistency for reliable research outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.