Description

2,4,6-Trichloro-5-Iodopyrimidine is a halogenated pyrimidine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring multiple reactive halogen sites, makes it an invaluable precursor for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and other biologically active compounds, particularly in nucleoside and nucleotide analog synthesis.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its pyrimidine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science applications.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and synthesizing novel heterocyclic libraries for screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its functionalizable halogen atoms.

Basic Information

Product Name	2,4,6-Trichloro-5-Iodopyrimidine
CAS No.	1137576-61-4
Molecular Formula	C4Cl3IN2
Molecular Weight	324.33 g/mol
Synonyms	5-Iodo-2,4,6-trichloropyrimidine; 2,4,6-Trichloro-5-iodo-pyrimidine; Pyrimidine, 2,4,6-trichloro-5-iodo-; 5-Iodo-2,4,6-trichloro-1,3-diazine
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichloro-5-Iodopyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.