Description

2,5-Dichloro-4-Iodopyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), nucleoside analogs, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral, anticancer, and other biologically active nucleoside analogs and small molecule drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its pyrimidine core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution.
• Material Science: Potential monomer or building block for creating specialized polymers and organic electronic materials.
• Academic & Industrial R&D: Essential reagent for methodological studies and library synthesis in medicinal and combinatorial chemistry.

Basic Information

Product Name	2,5-Dichloro-4-Iodopyrimidine
CAS No.	1137576-41-0
Molecular Formula	C4HCl2IN2
Molecular Weight	288.87 g/mol
Synonyms	4-Iodo-2,5-dichloropyrimidine; 2,5-Dichloro-4-iodopyrimidine; Pyrimidine, 2,5-dichloro-4-iodo-; 4-Iodo-2,5-dichloro-pyrimidine; 2,5-Dichloro-4-iodo-pyrimidine
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-Iodopyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.