Description

Kiss-1 (94-121) (Human) is a synthetic peptide fragment derived from the Kisspeptin-1 protein, a key regulator of the hypothalamic-pituitary-gonadal axis. This high-purity reference standard is critical for ensuring accuracy and reproducibility in endocrine and metabolic research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on reproductive biology, neuroendocrinology, and oncology research.

Application

• Biomedical Research: Used as a reference standard in studies investigating the role of kisspeptin in puberty, fertility, and hormone secretion.
• Assay Development & Validation: Essential for calibrating immunoassays (ELISA, RIA) and chromatographic methods (HPLC, LC-MS) for kisspeptin detection.
• Drug Discovery: Serves as a key reagent in high-throughput screening (HTS) for compounds targeting the GPR54 (KISS1R) receptor.
• Quality Control: Employed as an internal standard for the quality assurance of diagnostic kits and other peptide-based products.
• Academic Studies: Facilitates fundamental research in neurobiology, cancer metastasis (due to kisspeptin's role as a metastasis suppressor), and metabolic disorders.

Basic Information

Product Name	Kiss-1 (94-121) (Human)
CAS No.	1135442-77-1
Molecular Formula	C140H226N44O42S
Molecular Weight	3165.6 g/mol
Synonyms	Kisspeptin-10; Metastin (45-54); Kp-10; Kisspeptin-1 (112-121)-amide; hKisspeptin-10; KISS1 (112-121); TDNKRYNSFGLRF-NH2; Human KISS1 Gene Product 112-121
EINECS	Contact for details

Quality Control

Our Kiss-1 (94-121) (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Sequence	TDNKRYNSFGLRF-NH2
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.