Description

Ethyl 2-Chlorothieno[3,2-D]Pyrimidine-4-Carboxylate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting protein kinases for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for developing selective chemical probes to study biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies and novel heterocyclic chemistry.

Basic Information

Product Name	Ethyl 2-Chlorothieno[3,2-D]Pyrimidine-4-Carboxylate
CAS No.	1135299-23-8
Molecular Formula	C9H7ClN2O2S
Molecular Weight	242.68 g/mol
Synonyms	Ethyl 2-chlorothieno[3,2-d]pyrimidine-4-carboxylate; 2-Chlorothieno[3,2-d]pyrimidine-4-carboxylic acid ethyl ester; 1135299-23-8; Ethyl 2-chloro-thieno[3,2-d]pyrimidine-4-carboxylate; Thieno[3,2-d]pyrimidine-4-carboxylic acid, 2-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chlorothieno[3,2-D]Pyrimidine-4-Carboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.