Description

tert-Butyl 4-{4-[Amino(Hydroxyimino)Methyl]-2-Pyrimidinyl}Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in modern organic synthesis, particularly for constructing novel molecular scaffolds with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a precursor for synthesizing molecular probes used to study biological processes and target identification.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Heterocyclic Compound Library Synthesis: A valuable reagent for creating diverse libraries of pyrimidine and piperazine-containing compounds for high-throughput screening.

Basic Information

Product Name	tert-Butyl 4-{4-[Amino(Hydroxyimino)Methyl]-2-Pyrimidinyl}Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	1135283-52-1
Molecular Formula	C14H22N6O3
Molecular Weight	322.37 g/mol
Synonyms	tert-Butyl 4-[4-(amino-hydroxyimino-methyl)pyrimidin-2-yl]piperazine-1-carboxylate; 1-Boc-4-(4-amidoximyl-2-pyrimidinyl)piperazine; 4-[4-(Amino-hydroxyimino-methyl)-2-pyrimidinyl]-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-(4-(amino(hydroxyimino)methyl)pyrimidin-2-yl)piperazine-1-carboxylate; CAS 1135283-52-1; 1-Boc-4-(4-carbamimidoyl-2-pyrimidinyl)piperazine; 1-N-Boc-4-(4-amidoximyl-2-pyrimidinyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-{4-[Amino(Hydroxyimino)Methyl]-2-Pyrimidinyl}Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.