Description

2-Fluoro-5-Methoxybenzylamine Hydrochloride is a high-purity, functionalized benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, fluorine-substituted aromatic amine scaffold essential for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications ranging from drug discovery to specialty polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the fluorine and methoxy groups can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials due to its aromatic and polar functional groups.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation, labeling probes, and developing enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis organizations (CSOs) and CDMOs producing complex, bespoke organic molecules for clients.

Basic Information

Product Name	2-Fluoro-5-Methoxybenzylamine Hydrochloride
CAS No.	1134508-37-4
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	(2-Fluoro-5-methoxyphenyl)methanamine hydrochloride; 1-(2-Fluoro-5-methoxyphenyl)methanamine hydrochloride; 2-Fluoro-5-methoxybenzenemethanamine hydrochloride; 5-Methoxy-2-fluorobenzylamine hydrochloride; α-Amino-2-fluoro-5-methoxy toluene hydrochloride; Benzenemethanamine, 2-fluoro-5-methoxy-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxybenzylamine Hydrochloride undergoes rigorous analytical testing to ensure it meets the high standards required for research and industrial synthesis. Our quality assurance protocol includes multiple orthogonal methods to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request and provide full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.