Description

(5-Bromopyrimidin-2-Yl)Acetic Acid Ethyl Ester is a high-purity brominated pyrimidine derivative serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a valuable scaffold for designing molecular probes and enzyme inhibitors for biological target validation.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(5-Bromopyrimidin-2-Yl)Acetic Acid Ethyl Ester
CAS No.	1134327-91-5
Molecular Formula	C8H9BrN2O2
Molecular Weight	245.07 g/mol
Synonyms	Ethyl (5-bromopyrimidin-2-yl)acetate; 2-(5-Bromopyrimidin-2-yl)acetic acid ethyl ester; Ethyl 2-(5-bromopyrimidin-2-yl)acetate; (5-Bromo-2-pyrimidinyl)acetic acid ethyl ester; Acetic acid, 2-(5-bromopyrimidinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our (5-Bromopyrimidin-2-Yl)Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.