Description

4-Bromo-6-Methyl-2-Propan-2-Ylpyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, where it is used to introduce the pyrimidine core into target structures for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and liquid crystals.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-6-Methyl-2-Propan-2-Ylpyrimidine
CAS No.	1134263-20-9
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	4-Bromo-6-methyl-2-(propan-2-yl)pyrimidine; 4-Bromo-6-methyl-2-isopropylpyrimidine; 2-Isopropyl-4-bromo-6-methylpyrimidine; 4-Bromo-2-isopropyl-6-methylpyrimidine; 4-Bromo-6-methyl-2-(1-methylethyl)pyrimidine; Pyrimidine, 4-bromo-6-methyl-2-(1-methylethyl)-; 1134263-20-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Methyl-2-Propan-2-Ylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.