Description

2-Bromo-5-Fluoro-4-Thiocyanatoaniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, incorporating bromo, fluoro, and thiocyanate substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and sulfur-containing groups for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and heteroaryl structures.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its reactive functional groups.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Thiocyanatoaniline
CAS No.	1133115-25-9
Molecular Formula	C7H4BrFN2S
Molecular Weight	247.09 g/mol
Synonyms	4-Amino-2-bromo-5-fluorophenyl thiocyanate; 2-Bromo-5-fluoro-4-thiocyanato-benzenamine; 1-Amino-2-bromo-5-fluoro-4-thiocyanatobenzene; Benzenamine, 2-bromo-5-fluoro-4-thiocyanato-; 4-Thiocyanato-2-bromo-5-fluoroaniline; 2-Bromo-5-fluoro-4-isothiocyanatoaniline (tautomeric form); 2-Br-5-F-4-SCN-aniline (abbrev.)
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Thiocyanatoaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.